Invited Lecture at Joanneum, Graz (December 9, 2014)―At the FH Joanneum in Graz/Austria, Karsten Fehre―Medexter's Arden Syntax project leader―held a lecture named "Arden Syntax―An introduction; Technical Integration; Clinical decision support: Arden-Syntax-based applications" as part of the university's curriculum.

Invited Lecture on Critical and Adverse Events, Berlin (December 2, 2014)—CEO and Scientific Head Prof. Dr. Klaus-Peter Adlassnig was invited by Digital Health – Innovationstage Gesundheit in Berlin/Germany to hold a lecture on the monitoring of critical and adverse events.

Presentation at Nordic Mobile Healthcare Technology Congress, Copenhagen (November 26, 2014)—CEO and Scientific Head Prof. Dr. Klaus-Peter Adlassnig held a lecture on "Patient-Oriented Continuous Monitoring of Critical and Adverse Events" at the Nordic Mobile Healthcare Technology Congress in Copenhagen/Denmark.

Lecture on Arden Syntax in Osnabrück (November 20, 2014)―Medexter's Arden Syntax project leader Karsten Fehre held al lecture at the Osnabrück University of Applied Sciences in Osnabrück/Germany on "Arden Syntax―Core Concepts and Technical Integration".

Fuzzy Logic in an Automated HAI Surveillance System, Lyon (November 16, 2014)—At the 9th Healthcare Infection Society International Conference (HIS 2014) in Lyon/France, members of the Medexter team gave a talk on "The Use of Fuzzy Logic in an Automated Surveillance System".

Klaus-Peter Adlassnig elected Fellow of the American College of Medical Informatics (FACMI) (November 16, 2014)Medexter's CEO and Scientific Head Prof. Dr. Klaus-Peter Adlassnig was recognized for his accomplishments in the field of medical informatics by being elected Fellow of the American College of Medical Informatics (ACMI), Bethesda, MD, and is now eligible to use the designation FACMI. ACMI is an honorary College of elected Medical Informatics Fellows from the United States and abroad who have made significant and sustained contributions to the field of medical informatics and who have met rigorous scholarly scrutiny by their peers. The College originated in 1984 when five pioneers decided to establish an honorific society to recognize expertise in biomedical informatics. Today, there are nearly 300 Fellows, with 10–20 new Fellows elected each year when Voting Fellows of the College judge nominees during a formal election process. On November 16, 2014, the new Fellows were inducted into ACMI at ceremonies during the AMIA 2014 Annual Symposium in Washington, D.C.. The American College of Medical Informatics' Incantation was read to the inductees: "It has been said that the sweetest reward of a life of professional achievement is recognition by one's peers. Each of the persons recognized this evening has, by their sustained achievements, won the respect and admiration of their peers. Each of you, through your creativity, academic rigor, and perseverance, has brought recognition and honor to the discipline of Medical Informatics. Tonight, and from this point forward in time, that recognition and that honor, in some small measure, are returned to each of you. May this celebration of your achievements inspire you to yet greater contributions to Medical Informatics, for the betterment of all humanity."

Paper presented at APAMI conference, New Delhi (November 1–2, 2014)—Medexter's CEO and Scientific Head Professor Klaus-Peter Adlassnig presented a paper on "Service-Oriented Fuzzy-Arden-Syntax-Based Clinical Decision Support" at the APAMI 2014 Health IT Solutions conference in New Delhi/India. The paper was published in the Indian Journal of Medical Informatics.

Arden Syntax Version 2.10 ANSI-approved (October 31, 2014)—The latest version of the Health Level Seven (HL7) Arden Syntax for Medical Logic Systems was approved by the American National Standards Institute (ANSI). Amongst other improvements, the version's new feature ArdenML, an XML representation of Arden Syntax's medical logic modules (MLMs), allows the Arden Synax to be compatible with all other HL7 standards based on XML (HL7 version 3, VmR, and others).

HL7 Annual Meeting, Kassel (October 23, 2014)—At the Health Level Seven (HL7) Germany's Annual Meeting in Kassel, Germany, Karsten Fehre—Medexter's Arden Syntax project leader—gave a talk on "Wissen dokumentieren und teilen: Arden Syntax".

Meeting with Russian Healthcare Leaders (October 3, 2014)—LISAvienna hosted a presentation and networking event with a high-level delegation of physicians and management staff from the Russian healthcare system and seven Viennese medical technology and healthcare companies. Medexter's CEO and Scientific Head Prof. Dr. Klaus-Peter Adlassnig participated in the event and presented "Clinical decision support—Automated monitoring/analytics of critical and adverse events".

Medicine Safety Code Initiative (August 31, 2014)—A paper entitled "Towards a global IT system for personalized medicine: the Medicine Safety Code initiative" was co-authored by members of Medexter Healthcare and presented at the 25th European Medical Informatics Conference (MIE 2014) in Istanbul/Turkey.

Implementation Guide for Arden Syntax (August 25, 2014)An Implementation Guide for Arden Syntax, Release 1 was written by HL7 International's Arden Syntax Work Group and approved for publication by HL7 International. The guide's objective is to help knowledge engineers, clinicians, administrators, computer programmers and others to use the Arden Syntax to create clinical decision support (CDS) solutions. It includes instruction on how to represent different kinds of knowledge using medical logic modules (MLMs) (e.g., alerts/reminders, decision tables, flowcharts, clinical test result monitoring, public health surveillance), MLM templates and examples, as well as background material such as references to related scientific literature. Medexter regularly participates in the Arden Syntax Work Group and co-authored the implementation guide.

Arden Syntax: Technical Integration III (July 7, 2014)—Intelligent eHealth solutions often demand technical integration IIIpatient data from different sources such as hospital, laboratory, and intensive care information systems or—out of performance or legal reasons—a strict separation of patient data gathering and intelligent processing is necessary. In these cases, Medexter's Arden Syntax server, including its rule engine and its database connector, accesses a project-specific data warehouse (which can be quite general and extended). This data warehouse receives "raw" patient data through communication servers or import routines from any external data source (in HL7/XML/batch or other formats). The received data trigger the rule engine (when appropriate), and the data warehouse makes data available for further processing in the Arden Syntax server. The data warehouse can in return store the final or even the intermediate results generated by rule processing. These results may subsequently either be transferred back to the calling host application for presentation or—if the data warehouse is part of a separate solution—to the solution's presentation layer. The stored results may be used for reporting and benchmarking, or for data and knowledge mining. By introducing such an architecture, autonomous add-on clinical decision support systems are established. An example is Medexter's Moni system, which monitors and reports on hospital-acquired infections in intensive care units with adult and neonatal patients.

Arden Syntax: Technical Integration II (July 7, 2014)—The second form of interconnecting Medexter's suite of Artechnical integration IIden Syntax software with host systems and external patient data sources is to call MLMs and events through SOAP or RESTful web services, but to access patient data directly from data sources through a so-called server connector (being an add-on to the Arden Syntax server). This server connector can be used to query patient data through SOAP or RESTful web services that are offered by the host system to access its data, or it comes as a database connector that connects directly to a database to access data (e.g., SQL database). In addition, the server connector can also be developed in such a way as to access data in arbitrary formats (e.g., XML). Technically, the server connector is a template for realizing various operable connectors. Examples are (a) the connection of Medexter's Arden Syntax server with the EPIC hospital information system (via web services provided by EPIC), (b) with the VistA system by the Department of Veterans Affairs (again through web services, here provided by VistA), and (c) accessing SQL databases through Medexter's database connector to obtain patient data from routine patient databases or from databases for research (and teaching).

Arden Syntax: Technical Integration I (July 7, 2014)—The Arden Syntax server harbors the Arden Syntax medical logic modules (MLMs). These technical integrationknowledge packages are written, tested, and compiled using the integrated Arden Syntax development environment (IDE). To connect the server with host systems and data sources, Medexter offers three basic forms of technical integration into different health information technology (IT) environments. Using the first form of integration, MLM and event calls are realized by SOAP or RESTful web services, with the respective service also transferring the necessary data required for MLM processing. Examples are (a) the connection between Medexter's Arden Syntax server and Siemens' (Xetra: SIE, NYSE: SI, LSE: SIE, SWX: SIN) hospital information system via SOAP web services, and (b) calling of and providing data for the iPhone and iPad App Hepaxpert via RESTful web services.

Fuzziness in Healthcare-Associated Infection Monitoring (June 25, 2014)—At the Annual Meeting of the North American Fuzzy Information Processing Society (NAFIPS) that was held as part of the IEEE 2014 conference on Norbert Wiener in the 21st Century, our CEO and Scientific Head Prof. Dr. Klaus-Peter Adlassnig presented a paper on "Fuzziness in Healthcare-Associated Infection Monitoring and Surveillance". The paper was co-authored by members of the Medical University of Vienna.

Arden Syntax Lecture, Dortmund (June 5, 2014)—At the Department of Computer Science of the FH Dortmund (University of Applied Sciences and Arts) in Dortmund, Germany, Klaus-Peter Adlassnig, CEO and Scientific Head of Medexter Healthcare, gave overall three well received lectures on different topics: Firstly, an introductory lecture on Arden Syntax, its Fuzzy Logic component, ArdenML, as well as on possible technical integrations, secondly, about clincial decision support in practice, and thirdly, concerning the use of intelligent systems in healthcare and the question of responsibility.

eHealth Summit Austria 2014, Vienna (May 22–23, 2014)In the end of May, the eHealth Summit Austria took place P1040038 rin the picturesque setting of the Schönbrunn Palace in Vienna. Medexter participated in the event as exhibitor as part of the trade fair. Additionally, members of the Medexter Healthcare team contributed to the scientific conference in form of overall 6 lectures. Inspiring discussions about our approach and products as well as promising meetings with prospective customers ensued.

Scientific contributions at eHealth Summit Austria 2014, Vienna (May 22–23, 2014)Univ.-Prof. Dr. Klaus-Peter Adlassnig (CEO) and DI Karsten Fehre (research and development) held a workshop in cooperation with Univ.-Prof. Dr. Michael Binder (Medical University of Vienna) and Mag. Dr. Stefan Sabutsch (ELGA GmbH and head of HL7 Austria) on "HL7-Standards zur medizinischen Wissensverarbeitung: Arden-Syntax und ArdenML". Addressing the topic "mHealth and Telehealth", Dr. Philipp Meng presented a "Framework for Near-Field-Communication-Based Geo-Localization and Personalization for Android-Based Smartphones—Application in Hospital Environments". DI Alexander Seitinger participated in the finale of the conference's student competition with "An Arden-Syntax-Based Clinical Decision Support Framework for Medical Guidelines—Lyme Borreliosis as an Example". Talking about "Monitoring von unerwünschten Arzneimittelwirkungen – für Klinik, Qualitätsmanagement und Pharmakovigilanz", CEO Prof. Dr. Klaus-Peter Adlassnig contributed to the ongoing discussion regarding "Medication Safety". Additionally, a presentation entitled "Towards a Global IT System for Personalized Medicine: The Medicine Safety Code Initiative" was given by Mag. Dr. Matthias Samwald on the topic "eMedication and Drug Safety". The final highlight of Medexter's presentation activities was a software demonstration by CEO Prof. Dr. Klaus-Peter Adlassnig showing the possibilities of "Healthcare-Associated Infection Surveillance and Bedside Alerts" using the surveillance tool Moni (Monitoring of Nosocomial Infections)an application developed by Medexter Healthcare and in use in several hospitals.

Arden Syntax Training, Vienna (May 21, 2014)In cooperation with HL7 Austria, Medexter hosted a one-day Arden Syntax training course at the FH Technikum in Vienna. Attendees were Germans and Austrians who were either interested beginners in the Arden Syntax or were already using it and looking for a more detailed insight into the field. Contents discussed included Arden Syntax, Fuzzy Arden Syntax, ArdenML, software components, technical integration, and clinical applications. Find material here.

Conference on Data Safety in Healthcare, Berlin (May 13, 2014)—At the 2nd GDD-Fachtagung on data safety in healthcare "Datenschutz und Datensicherheit im Gesundheitswesen", CEO Prof. Dr. Klaus-Peter Adlassnig contributed to the discussion regarding the issue of responsibility for intelligent and autonomous IT systems in his lecture "Intelligente und autonome Systeme in der Medizin - Wer trägt die Verantwortung?".

ConhIT 2014, Berlin (May 6–8, 2014)—For the fifth time, Medexter Healthcare attended conhit 2014the Connecting Healthcare IT (conhIT) trade fair in Berlin/Germany. Medexter's clinical decision support products where presented in our booth and interesting conversations as well as intensive discussions with present and prospective customers took place. Additionally, the Medexter booth was part of the guided tour "Interoperability" with focus on applications, where selected exhibitors showed their topic-related IT solutions. On top of that, CEO and Scientific Head Prof. Dr. Klaus-Peter Adlassnig talked about "HL7 standards for medical knowledge representation: Arden Syntax and ArdenML." at the conhIT industry session, a forum for industrial partners and exhibitors to present their products, applications and experiences.

Arden Syntax Version 2.10 (May 6, 2014)—Successfully balloted by Health Level Seven (HL7) International,ArdenML the latest Arden Syntax version contains a new feature: ArdenML, an XML representation of Arden Syntax's medical logic modules (MLMs). Medexter Healthcare offers cross compilation/transformation between the text-based and the XML-based representations of the Arden Syntax MLMs. Thus, Arden Syntax is now compatible with all other HL7 standards based on XML (HL7 version 3, VmR, and others). As a further benefit, it is now possible for developers to use available XML tools in their work with MLMs.

ConhIT Satellite Event, Berlin (May 5, 2014)—At the conhIT 2014 satellite event organized by the GMDS and BVMI in Berlin/Germany, CEO and Scientific Head Prof. Dr. Klaus-Peter Adlassnig held an invited lecture on "Progress on Arden Syntax: Fuzziness, technical integration, and ArdenML.".

Pharmacogenomic Decision Support (May 2, 2014)—In cooperation with the Medical University of Vienna/Austria and the University of Pittsburgh/U.S.A, members of Medexter Healthcare published a paper in PLOS ONE about "An Ontology-Based, Mobile-Optimized System for Pharmacogenomic Decision Support at the Point-of-Care.".

Arden Syntax Work Group (March 21, 2014)—The Arden Syntax for Medical Logic Systems Version 2.10 was prepared for balloting in the next ballot cycle of Health Level Seven (HL7) International in May 2014. This version was developed with extended contributions by the Medexter team being part of HL7’s Arden Syntax Work Group. At the same time, an Implementation Guide for Arden Syntax, Release 1, was also submitted for balloting. Again, members of Medexter contributed extensively to this document.

Invited Lecture FH Technikum, Vienna (March 13, 2014)—CEO and Scientific Head Prof. Dr. Klaus-Peter Adlassnig gave an invited talk at the FH Technikum in Vienna on "Clinical decision support in practice".

IFIC Congress, Malta (March 12-15, 2014)—In cooperation with members of the Medical University of Vienna, members of Medexter Healthcare presented "Intelligent electronic tools for automated surveillance and feedback, for audit and networking. A significant step towards evidence-based IPC in intensive care." at the 14th Congress of the International Federation of Infection Control (IFIC2014) in St. Julian's/Malta.

HEALTHINF 2014, Angers (March 3–6, 2014)—At the 7th International Conference on Health Informatics that took place in Angers/France, members of the Medexter team presented a "Plea for Use of Intelligent Information and Communication Technologies in Healthcare Institutions".



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