Knowledge-based interpretive analysis for hepatitis A, B, and C serology test results
Hepaxpert is a software solution that allows precise and exhaustive interpretations of hepatitis serology test results. To achieve this goal, a clinically relevant, textual interpretation of the obtained results is automatically generated and displayed or added to the final laboratory report.
The automatic interpretation of findings is based on the qualitative test results for hepatitis A serology (anti-HAV, IgM anti-HAV, and HAV-RNA); the qualitative test results for hepatitis B serology (HBsAg, anti-HBs, anti-HBc, IgM anti-HBc, HBeAg, anti-HBe) and the quantitative test result for anti-HBs titer; and the qualitative test results for hepatitis C serology (anti-HCV and HCV-RNA).
The knowledge base of Hepaxpert contains rule packages to interpret all possible—even extremely rare and complex—combinations of hepatitis serology test results. Hepaxpert automatically interprets the result of these tests, without the need of any additional patient history, biochemical, or clinical data.
The interpretive texts help physicians-in-training as well as experienced physicians to understand the often complex serologic findings, and thus promote quality assurance in diagnosis and save valuable time.
The automatically generated interpretive reports include a detailed analysis with regard to virus exposure, immunity, stage of illness, prognosis, and infectiousness. A quantitative anti-HBs titer test result may add recommendations on hepatitis vaccination.
Available applications & integration
Hepaxpert can be integrated into various healthcare information systems such as hospital and laboratory information systems (HISs, LISs), medical practice software systems, as well as into web-based systems for telemedical or central clinical decision support (see www.teleiatros.com).
- A simple mouse-click can provide a textual, clinically-oriented interpretation of the test results on the laboratory result screen of an HIS.
- A printed or electronically distributed laboratory report of a LIS can be augmented by an automatically generated and inserted interpretive text.
- Telemedical or central clinical decision support can be offered by using any standard web-browser or as automated server-request-based web service.
- Hepaxpert may also be downloaded as iPhone or iPad App.